Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pattern and progression of cognitive decline in Alzheimer's disease: role of premorbid intelligence and ApoE genotype.

Dementia and geriatric cognitive disorders - 1 Jan 2007

Bracco Laura, Piccini Carolina, Baccini Michela, Bessi Valentina, Biancucci Federica, Nacmias Benedetta, Bagnoli Silvia, Sorbi Sandro

Abstract excerpt

BACKGROUND/AIMS: Because of controversial results across studies, we evaluated the predictive value of premorbid intelligence and the apolipoprotein E (ApoE) genotype on baseline and progression of cognitive performance in Alzheimer's disease (AD). METHODS: Eighty-five mild AD cases, ApoE genotyped and included in a longitudinal cliniconeuropsychological-genetic study, underwent a premorbid intelligence test and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Frequency
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoprotein E4

Share to Cognition Disorders

Share to Disease Progression

Share to Intelligence

Share to Neuropsychological Tests

Share to Severity of Illness Index

Source

Identifiers

PMID: 18025782
DOI: 10.1159/000111081

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pattern and progression of cognitive decline in Alzheimer's disease: role of premorbid intelligence and ApoE genotype.PMID 18025782Read ↗

Alzheimer's disease genetic risk and cognitive reserve in relationship to long-term cognitive trajectories among cognitively normal individuals.Semantic proximity Read ↗

Apolipoprotein E moderates the association between Non-<i>APOE</i>Polygenic Risk Score for Alzheimer’s Disease and Aging on Preclinical Cognitive FunctionSemantic proximity Read ↗

Influence of apolipoprotein E varepsilon4 on rates of cognitive and functional decline in mild cognitive impairment.Semantic proximity Read ↗

Amyloid-β and APOE genotype predict memory decline in cognitively unimpaired older individuals independently of Alzheimer's disease polygenic risk score.Semantic proximity Read ↗

Cognitive domain decline in healthy apolipoprotein E epsilon4 homozygotes before the diagnosis of mild cognitive impairment.Semantic proximity Read ↗

The association of APOE ε4 with cognitive function over the adult life course and incidence of dementia: 20 years follow-up of the Whitehall II study.Semantic proximity Read ↗

Genetic effects on longitudinal cognitive decline during the early stages of Alzheimer's diseaseSemantic proximity Read ↗

APOE genotype, memory test performance, and the risk of Alzheimer's disease in the Canadian Study of Health and Aging.Semantic proximity Read ↗

Preclinical memory decline in cognitively normal apolipoprotein E-epsilon4 homozygotes.Semantic proximity Read ↗

Memory performance and the apolipoprotein E polymorphism in a community sample of middle-aged adults.Semantic proximity Read ↗

Neuropsychological function and apolipoprotein E genotype in the preclinical detection of Alzheimer's disease.Semantic proximity Read ↗

Longitudinal Modeling of Age-Related Memory Decline and the<i>APOE</i>ε4 EffectSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.