A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells.

doi:10.1084/jem.20061865

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Article

A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells.

The Journal of experimental medicine - 26 Nov 2007

Lichterfeld Mathias, Kavanagh Daniel G, Williams Katie L, Moza Beenu, Mui Stanley K, Miura ToshiYuki, Sivamurthy Rohini, Allgaier Rachel, Pereyra Florencia, Trocha Alicja, Feeney Margaret, Gandhi Rajesh T, Rosenberg Eric S, Altfeld Marcus, Allen Todd M, Allen Rachel, Walker Bruce D, Sundberg Eric J, Yu Xu G

Abstract excerpt

Viral mutational escape can reduce or abrogate recognition by the T cell receptor (TCR) of virus-specific CD8+ T cells. However, very little is known about the impact of cytotoxic T lymphocyte (CTL) epitope mutations on interactions between peptide-major histocompatibility complex (MHC) class I complexes and MHC class I receptors expressed on other cell types. Here, we analyzed a variant of the immunodominant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18025130
DOI: 10.1084/jem.20061865
PMCID: PMC2118510

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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