Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational escape in HIV-1 CTL epitopes leads to increased binding to inhibitory myelomonocytic MHC class I receptors.

PloS one - 8 Dec 2010

Yang Yue, Huang Jinghe, Toth Ildiko, Lichterfeld Mathias, Yu Xu G

Abstract excerpt

Escape mutations in HIV-1 cytotoxic T cell (CTL) epitopes can abrogate recognition by the TCR of HIV-1-specific CD8+ T cells, but may also change interactions with alternative MHC class I receptors. Here, we show that mutational escape in three HLA-A11-, B8- and B7- restricted immunodominant HIV-...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B7-1 Antigen
Share to CD8-Positive T-Lymphocytes
Share to Genes, MHC Class I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-B Antigens

Share to Lipopolysaccharide Receptors

Share to Monocytes

Share to Receptors, Immunologic

Share to T-Lymphocytes, Cytotoxic

Source

Open in PubMed Open full text

Identifiers

PMID: 21170342
DOI: 10.1371/journal.pone.0015084
PMCID: PMC2999561

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21170342-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational escape in HIV-1 CTL epitopes leads to increased binding to inhibitory myelomonocytic MHC class I receptors.PMID 21170342Read ↗

A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells.Semantic proximity Read ↗

T cell receptor recognition motifs govern immune escape patterns in acute SIV infection.Semantic proximity Read ↗

Escape mutations in HIV infection and its impact on CD8+ T cell responses.Semantic proximity Read ↗

Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte response.Semantic proximity Read ↗

Reversion of immune escape HIV variants upon transmission: insights into effective viral immunity.Semantic proximity Read ↗

Role of CD8+ T Cells in the Selection of HIV-1 Immune Escape Mutations.Semantic proximity Read ↗

MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.Semantic proximity Read ↗

Widespread impact of HLA restriction on immune control and escape pathways of HIV-1.Semantic proximity Read ↗

How HIV evades CTL recognition.Semantic proximity Read ↗

Virus variation, escape from cytotoxic T lymphocytes and human retroviral persistence.Semantic proximity Read ↗

De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection.Semantic proximity Read ↗

CTL escape and increased viremia irrespective of HIV-specific CD4+ T-helper responses in two HIV-infected individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.