Article
Human pre-elafin inhibits a Pseudomonas aeruginosa-secreted peptidase and prevents its proliferation in complex media.
Antimicrobial agents and chemotherapy - 1 Feb 2008
Bellemare Audrey, Vernoux Nathalie, Morisset Dany, Bourbonnais Yves
Abstract excerpt
Pseudomonas aeruginosa is a life-threatening opportunist human pathogen frequently associated with lung inflammatory diseases, namely, cystic fibrosis. Like other species, this gram-negative bacteria is increasingly drug resistant. During the past decade, intensive research efforts have been focused on the identification of natural innate defense molecules with broad antimicrobial activities, collectively known...
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