Article

Proteolytically activated antibacterial toxins inhibit the growth of diverse Gram-positive bacteria

2025-04-13

Abstract excerpt

Many species of bacteria produce small-molecule antibiotics that enter and kill a wide range of competitor microbes. However, diffusible antibacterial proteins that share this broad-spectrum activity are not known to exist. Here, we report a family of proteins widespread in Gram-positive bacteria that display potent antibacterial activity against a diverse range of target organisms. Upon entering susceptible cells...

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Literature Corpus work: 8bca59a9-48c9-5fb0-b32e-14334195d34a
DOI: 10.1101/2025.04.13.648598

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