Article
Differentiation and Ig-allele switch in cell line WEHI-231.
Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2007
Spillmann Freia J X, Beck-Engeser Gabriele, Wabl Matthias
Abstract excerpt
Because of its susceptibility to apoptosis upon Ag receptor cross-linking and lack of IgD expression, cells of the mouse cell line WEHI-231 have been classified as immature B cells. In this study we show that early freezings of the WEHI-231 line express IgD but not CD93, which classifies the cells as more similar to mature B cells. Another, later line obviously has differentiated in culture and has all the...
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