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Article

Loss of CD23 is a consequence of B-cell activation. Implications for the analysis of B-cell lineages.

Annals of the New York Academy of Sciences - 4 May 1992

Rabin E, Cong Y Z, Wortis H H

Abstract excerpt

When splenic CD5- B cells are stimulated with antiimmunoglobulin they become CD5+ and have a prolonged in vitro life. Further treatment with IL-6 induces a loss of surface CD23 and IgD; that is, they resemble freshly isolated peritoneal CD5+ cells. These data suggest that the CD5 phenotype is induced after sIg-mediated B-cell activation. Additional support for this view arises from the observation that the loss...

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Source

Identifiers

PMID: 1376028
DOI: 10.1111/j.1749-6632.1992.tb24602.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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