Article
Reversal of Blimp-1-mediated apoptosis by A1, a member of the Bcl-2 family.
European journal of immunology - 1 Sept 1999
Knödel M, Kuss A W, Lindemann D, Berberich I, Schimpl A
Abstract excerpt
Blimp-1 (B lymphocyte-induced maturation protein 1) is strongly expressed during the late stages of B cell differentiation to immunoglobulin-secreting plasma cells. Overexpression of Blimp-1 in B lymphoma cells has been reported to induce either growth arrest and cell death or Ig secretion and terminal differentiation, depending on the developmental stage of the recipient lymphomas. By using a retroviral...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
