Article
PYP-1, inorganic pyrophosphatase, is required for larval development and intestinal function in C. elegans.
FEBS letters - 27 Nov 2007
Ko Kyung Min, Lee Wonhae, Yu Jae-Ran, Ahnn Joohong
Abstract excerpt
Inorganic pyrophosphatase (PPase) catalyzes the hydrolysis of inorganic pyrophosphate (PPi) into phosphate (Pi), which provides a thermodynamic driving force for important biosynthetic reactions. The nematode Caenorhabditis elegans gene C47E12.4 encodes a PPase (PYP-1) which shows 54% amino acid identity with human PPase. PYP-1 exhibits specific enzyme activity and is mainly expressed in the intestinal and...
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