Caenorhabditis elegans neprilysin NEP-1: an effector of locomotion and pharyngeal pumping.

doi:10.1016/j.jmb.2005.06.063

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Article

Caenorhabditis elegans neprilysin NEP-1: an effector of locomotion and pharyngeal pumping.

Journal of molecular biology - 16 Sept 2005

Spanier Britta, Stürzenbaum Stephen R, Holden-Dye Lindy M, Baumeister Ralf

Abstract excerpt

The control of signal peptide activity by cell surface proteases is one of the main factors that regulate the development and behaviour of organisms. In mammals, neprilysins (NEPs) are known to play a key role in these processes and their inactivation can initiate cellular disorganisation, which in turn may lead to prostate cancer or Hirschsprung disease. Although the proteome of the nematode Caenorhabditis...

Topics

Amino Acid Sequence
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cloning, Molecular
Electrophysiology
Green Fluorescent Proteins
Locomotion
Molecular Sequence Data
Mutation
Neprilysin
Neurons
Neuropeptides
Pharyngeal Muscles
Sequence Homology, Amino Acid
Serotonin

Source

Open in PubMed

Identifiers

PMID: 16081104
DOI: 10.1016/j.jmb.2005.06.063

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