Inositol polyphosphate multikinase IPMK-1 regulates development through IP3/calcium signaling in Caenorhabditis elegans.

doi:10.1016/j.ceca.2020.102327

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Inositol polyphosphate multikinase IPMK-1 regulates development through IP3/calcium signaling in Caenorhabditis elegans.

Cell calcium - 1 Jan 2021

Yang Zhong-Lin, Chen Jian-Ning, Lu Yu-Yang, Lu Min, Wan Qin-Li, Wu Gui-Sheng, Luo Huai-Rong

Abstract excerpt

Inositol polyphosphate multikinase (IPMK) is a conserved protein that initiates the production of inositol phosphate intracellular messengers and is critical for regulating a variety of cellular processes. Here, we report that the C. elegans IPMK-1, which is homologous to the mammalian inositol polyphosphate multikinase, plays a crucial role in regulating rhythmic behavior and development. The deletion mutant...

Topics

Amino Acid Sequence
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Calcium
Calcium Signaling
Defecation
Embryonic Development
Gene Deletion
Inositol 1,4,5-Trisphosphate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Intracellular Space

Mutation

Organ Specificity

Phenotype

Phosphotransferases

Phosphotransferases (Alcohol Group Acceptor)

Source

Open in PubMed

Identifiers

PMID: 33316585
DOI: 10.1016/j.ceca.2020.102327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-33316585-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inositol polyphosphate multikinase IPMK-1 regulates development through IP3/calcium signaling in Caenorhabditis elegans.PMID 33316585Read ↗

The inositol trisphosphate receptor regulates a 50-second behavioral rhythm in C. elegans.Semantic proximity Read ↗

Oscillatory Ca2+ signaling in the isolated Caenorhabditis elegans intestine: role of the inositol-1,4,5-trisphosphate receptor and phospholipases C beta and gamma.Semantic proximity Read ↗

Regulated disruption of inositol 1,4,5-trisphosphate signaling in Caenorhabditis elegans reveals new functions in feeding and embryogenesis.Semantic proximity Read ↗

Intestinal Ca2+ wave dynamics in freely moving C. elegans coordinate execution of a rhythmic motor program.Semantic proximity Read ↗

IPMK-1 (inositol phosphate multikinase) is required for integrin adhesion complex organization and muscle cell adhesion in Caenorhabditis elegans.Semantic proximity Read ↗

FLR-4, a novel serine/threonine protein kinase, regulates defecation rhythm in Caenorhabditis elegans.Semantic proximity Read ↗

Genetic analysis of IP3 and calcium signalling pathways in C. elegans.Semantic proximity Read ↗

A calcium wave mediated by gap junctions coordinates a rhythmic behavior in C. elegans.Semantic proximity Read ↗

PYP-1, inorganic pyrophosphatase, is required for larval development and intestinal function in C. elegans.Semantic proximity Read ↗

PIKI-1, a class II PI 3-kinase, functions in endocytic trafficking.Semantic proximity Read ↗

PIKI-1, a class II phosphatidylinositol 3-kinase, functions in endocytic traffickingSemantic proximity Read ↗

Multiple Functions and Dynamic Activation of MPK-1 Extracellular Signal-Regulated Kinase Signaling in<i>Caenorhabditis elegans</i>Germline DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.