Article

The <i>C. elegans</i> ASPP homolog APE-1 is a junctional protein phosphatase 1 modulator

2022-02-18

Abstract excerpt

How serine/threonine phosphatases are spatially and temporally tuned by regulatory subunits is a fundamental question in cell biology. Ankyrin repeat, SH3 domain, proline-rich-region-containing proteins (ASPPs) are protein phosphatase 1 (PP1) binding partners associated with cardiocutaneous diseases. ASPPs localize PP1 to cell-cell junctions, but how ASPPs localize and whether they regulate PP1 activity in vivo i...

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Literature Corpus work: b84d5595-5707-5e1f-95fc-2f426bd57af9
DOI: 10.1101/2022.02.15.480428

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