Article

PIKI-1, a class II phosphatidylinositol 3-kinase, functions in endocytic trafficking

2025-05-23

Abstract excerpt

Membrane trafficking, including endocytosis and exocytosis, is a complex process that is coordinated by trafficking-associated proteins, cargo molecules, the cytoskeleton, and membrane lipid composition. The NIMA-related kinases NEKL-2 (human NEK8/9) and NEKL-3 (human NEK6/7) are conserved regulators of membrane trafficking in Caenorhabditis elegans and are required for successful molting. Through a genetic appro...

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Literature Corpus work: 578b35e0-0cf8-586f-895d-f473089f8966
DOI: 10.1101/2025.05.22.655458

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