Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overlapping expression patterns and functions of three paralogous P5B ATPases in Caenorhabditis elegans.

PloS one - 1 Jan 2018

Zielich Jeffrey, Tzima Elena, Schröder Eva Ayla, Jemel Faten, Conradt Barbara, Lambie Eric J

Abstract excerpt

P5B ATPases are present in the genomes of diverse unicellular and multicellular eukaryotes, indicating that they have an ancient origin, and that they are important for cellular fitness. Inactivation of ATP13A2, one of the four human P5B ATPases, leads to early-onset Parkinson's disease (Kufor-Rakeb Syndrome). The presence of an invariant PPALP motif within the putative substrate interaction pocket of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to Animals, Genetically Modified

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Caenorhabditis elegans

Share to Caenorhabditis elegans Proteins

Share to Cell Movement

Share to Gene Expression Regulation, Enzymologic

Share to Luminescent Proteins

Share to Organelles

Source

Open in PubMed Open full text

Identifiers

PMID: 29547664
DOI: 10.1371/journal.pone.0194451
PMCID: PMC5856429

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overlapping expression patterns and functions of three paralogous P5B ATPases in Caenorhabditis elegans.PMID 29547664Read ↗

The CATP-8/P5A-type ATPase functions in multiple pathways during neuronal patterning.Semantic proximity Read ↗

The CATP-8/P5A-type ATPase functions in multiple pathways during neuronal patterningSemantic proximity Read ↗

The P-type ATPase CATP-1 is a novel regulator of C. elegans developmental timing that acts independently of its predicted pump function.Semantic proximity Read ↗

The C. elegans P4-ATPase TAT-1 regulates lysosome biogenesis and endocytosis.Semantic proximity Read ↗

WormTagDB: a systematic survey of endogenously tagged proteins in Caenorhabditis elegans and roadmap toward the tagged proteome.Semantic proximity Read ↗

Disease-related myotubularins function in endocytic traffic in Caenorhabditis elegans.Semantic proximity Read ↗

Parkinson disease related ATP13A2 evolved early in animal evolutionSemantic proximity Read ↗

Protein phosphatase 2A is crucial for sarcomere organization in Caenorhabditis elegans striated muscle.Semantic proximity Read ↗

Genetic analysis of the myotubularin family of phosphatases in Caenorhabditis elegans.Semantic proximity Read ↗

The zebrafish homologue of Parkinson's disease ATP13A2 is essential for embryonic survival.Semantic proximity Read ↗

IPMK-1 (inositol phosphate multikinase) is required for integrin adhesion complex organization and muscle cell adhesion in Caenorhabditis elegans.Semantic proximity Read ↗

eat-5 and unc-7 represent a multigene family in Caenorhabditis elegans involved in cell-cell coupling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.