Article
Thiamine pyrophosphate biosynthesis and transport in the nematode Caenorhabditis elegans.
Genetics - 1 Oct 2004
de Jong Liesbeth, Meng Yan, Dent Joseph, Hekimi Siegfried
Abstract excerpt
Thiamine (vitamin B1) is required in the diet of animals, and thiamine deficiency leads to diseases such as beri-beri and the Wernicke-Korsakoff syndrome. Dietary thiamine (vitamin B1) consists mainly of thiamine pyrophosphate (TPP), which is transformed into thiamine by gastrointestinal phosphatases before absorption. It is believed that TPP itself cannot be transported across plasma membranes in significant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.