Article
High prevalence of Foxp3 and IL17 in MMR-proficient colorectal carcinomas.
Gut - 1 Jun 2008
Le Gouvello S, Bastuji-Garin S, Aloulou N, Mansour H, Chaumette M-T, Berrehar F, Seikour A, Charachon A, Karoui M, Leroy K, Farcet J-P, Sobhani I
Abstract excerpt
BACKGROUND AND AIMS: Colorectal cancer (CRC) harbours different types of DNA alterations, including microsatellite instability (MSI). Cancers with high levels of MSI (MSI-H) are considered to have a good prognosis, probably related to lymphocyte infiltration within tumours. The aim of the present study was to characterise the intratumoural expression of markers associated with the antitumour immune response in...
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