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Regulatory T cells in inflammatory bowel diseases and colorectal cancer.

World journal of gastroenterology - 28 Oct 2012

Műzes Györgyi, Molnár Béla, Sipos Ferenc

Abstract excerpt

Regulatory T cells (T(regs)) are key elements in immunological self-tolerance. The number of T(regs) may alter in both peripheral blood and in colonic mucosa during pathological circumstances. The local cellular, microbiological and cytokine milieu affect immunophenotype and function of T(regs). Forkhead box P3+ T(regs) function shows altered properties in inflammatory bowel diseases (IBDs). This alteration of...

Topics

Animals
Cell Transformation, Neoplastic
Colitis, Ulcerative
Colon
Colorectal Neoplasms
Crohn Disease
Humans
Inflammation Mediators
Intestinal Mucosa
Phenotype
Signal Transduction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

T-Lymphocytes, Regulatory

Tumor Escape

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Open in PubMed Open full text

Identifiers

PMID: 23155308
DOI: 10.3748/wjg.v18.i40.5688
PMCID: PMC3484336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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