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Article

Opposing roles by KRAS and BRAF mutation on immune cell infiltration in colorectal cancer - possible implications for immunotherapy.

British journal of cancer - 1 Jan 2024

Edin Sofia, Gylling Björn, Li Xingru, Stenberg Åsa, Löfgren-Burström Anna, Zingmark Carl, van Guelpen Bethany, Ljuslinder Ingrid, Ling Agnes, Palmqvist Richard

Abstract excerpt

BACKGROUND: The immune response has important clinical value in colorectal cancer (CRC) in both prognosis and response to immunotherapy. This study aims to explore tumour immune cell infiltration in relation to clinically well-established molecular markers of CRC. METHODS: Multiplex immunohistochemistry and multispectral imaging was used to evaluate tumour infiltration of cytotoxic T cells (CD8+), Th1 cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38040818
DOI: 10.1038/s41416-023-02483-9
PMCID: PMC10781968

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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