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Systemic inflammatory response in colorectal cancer is associated with tumour mismatch repair and impaired survival

29 Nov 2024

Abstract excerpt

Abstract The systemic inflammatory response (SIR), defined as elevated levels of circulating C-reactive protein (CRP), is an important predictor of impaired survival in colorectal cancer. The aim of this study was to explore the prognostic role of SIR and its association with tumour mismatch repair status and the immune response. Immune activity profiles of mononuclear cells isolated from CRC tissues and blood in...

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PMID: 39613865
DOI: 10.1038/s41598-024-80803-6

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