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Article

Reduced DTNBP1 (dysbindin-1) mRNA in the hippocampal formation of schizophrenia patients.

Schizophrenia research - 1 Jan 2008

Weickert Cynthia Shannon, Rothmond Debora A, Hyde Thomas M, Kleinman Joel E, Straub Richard E

Abstract excerpt

Genetic and molecular studies indicate that dysbindin-1 plays a role in the pathophysiology of schizophrenia. We examined dysbindin-1 mRNA in the hippocampal formation of patients with schizophrenia and found reduced expression in dentate granule and polymorph cells and in hippocampal field CA3, but not in CA1. Furthermore, there were positive correlations between dysbindin-1 mRNA and expression of synaptic...

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Source

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Identifiers

PMID: 17961984
DOI: 10.1016/j.schres.2007.05.041
PMCID: PMC2246024

Genes

DTNBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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