Article
The dysbindin gene (DTNBP1) and schizophrenia: no support for an association in the Korean population.
Neuroscience letters - 23 Oct 2006
Joo Eun-Jeong, Lee Kyu-Young, Jeong Seong Hoon, Ahn Yong-Min, Koo Young Jin, Kim Yong Sik
Abstract excerpt
The dysbindin gene (DTNBP1) is located in chromosome 6p22.3, one of the regions of positive linkage for schizophrenia. A strong genetic association between DTNBP1 and schizophrenia has been replicated through many recent studies. In particular, dysbindin protein has been found to play a role in the glutamate neural transmission in the brain. In this study, we attempted to replicate the previously reported...
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