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Article

Dysbindin-1C is required for the survival of hilar mossy cells and the maturation of adult newborn neurons in dentate gyrus.

The Journal of biological chemistry - 17 Oct 2014

Wang Hao, Yuan Yefeng, Zhang Zhao, Yan Hui, Feng Yaqin, Li Wei

Abstract excerpt

DTNBP1 (dystrobrevin-binding protein 1), which encodes dysbindin-1, is one of the leading susceptibility genes for schizophrenia. Both dysbindin-1B and -1C isoforms are decreased, but the dysbindin-1A isoform is unchanged in schizophrenic hippocampal formation, suggesting dysbindin-1 isoforms may have distinct roles in schizophrenia. We found that mouse dysbindin-1C, but not dysbindin-1A, is localized in the...

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Identifiers

PMID: 25157109
DOI: 10.1074/jbc.M114.590927
PMCID: PMC4200260

Genes

DTNBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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