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Article

Is the dysbindin gene (DTNBP1) a susceptibility gene for schizophrenia?

Schizophrenia bulletin - 1 Oct 2005

Williams Nigel M, O'Donovan Michael C, Owen Michael J

Abstract excerpt

Over recent years the gene DTNBP1 (chromosome 6p24-22) has emerged as one of the most promising candidate genes for schizophrenia. In this article, we review the current genetic evidence that implicates DTNBP1 as a schizophrenia-susceptibility gene. While there is now impressive support from genetic association studies, it is important to remain aware that the actual DTNBP1 susceptibility variants have not been...

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Source

Identifiers

PMID: 16166606
DOI: 10.1093/schbul/sbi061

Genes

DTNBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Is the dysbindin gene (DTNBP1) a susceptibility gene for schizophrenia?PMID 16166606Read ↗

The DTNBP1 (dysbindin) gene contributes to schizophrenia, depending on family history of the disease.Semantic proximity Read ↗

The dysbindin gene (DTNBP1) and schizophrenia: no support for an association in the Korean population.Semantic proximity Read ↗

Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia.Semantic proximity Read ↗

No evidence for association of the dysbindin gene [DTNBP1] with schizophrenia in an Irish population-based study.Semantic proximity Read ↗

Analysis of HapMap tag-SNPs in dysbindin (DTNBP1) reveals evidence of consistent association with schizophrenia.Semantic proximity Read ↗

Dysbindin-1 and schizophrenia: from genetics to neuropathology.Semantic proximity Read ↗

Dysbindin gene (DTNBP1) and schizophrenia in Korean population.Semantic proximity Read ↗

Association study of DTNBP1 with schizophrenia in a US sample.Semantic proximity Read ↗

Dysbindin (DTNBP1) and the biogenesis of lysosome-related organelles complex 1 (BLOC-1): main and epistatic gene effects are potential contributors to schizophrenia susceptibility.Semantic proximity Read ↗

DTNBP1 (Dystrobrevin binding protein 1) and schizophrenia: association evidence in the 3' end of the gene.Semantic proximity Read ↗

A polymorphism in the dysbindin gene (DTNBP1) associated with multiple psychiatric disorders including schizophrenia.Semantic proximity Read ↗

An update on the genetics of schizophrenia.Semantic proximity Read ↗

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