Article
Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain.
Archives of general psychiatry - 1 Jun 2004
Weickert Cynthia Shannon, Straub Richard E, McClintock Benjamin W, Matsumoto Mitsuyuki, Hashimoto Ryota, Hyde Thomas M, Herman Mary M, Weinberger Daniel R, Kleinman Joel E
Abstract excerpt
CONTEXT: The schizophrenia-susceptibility gene dysbindin (DTNBP1 on 6p22.3) encodes a neuronal protein that binds to beta-dystrobrevin and may be part of the dystrophin protein complex. Little is known about dysbindin expression in normal or schizophrenic brain. OBJECTIVES: To determine whether brain regions implicated in schizophrenia express dysbindin and whether abnormal levels of dysbindin messenger RNA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
