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Article

Dysbindin-1 and schizophrenia: from genetics to neuropathology.

The Journal of clinical investigation - 1 May 2004

Owen Michael J, Williams Nigel M, O'Donovan Michael C

Abstract excerpt

The gene encoding dysbindin-1 has recently been implicated in susceptibility to schizophrenia. In this issue of the JCI, Talbot et al. show that, contrary to expectations, dysbindin-1 is located presynaptically in glutamatergic neurons and is reduced at these locations in schizophrenia. Further studies of dysbindin-1 and the proteins with which it interacts can be expected to throw light on the pathogenesis of...

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Identifiers

PMID: 15124015
DOI: 10.1172/JCI21470
PMCID: PMC398436

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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