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Free Interleukin (IL)-18 levels, and the impact of IL18 and IL18BP genetic variation, in CHD patients and healthy men.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2007

Thompson Simon R, Novick Daniela, Stock Carmel J, Sanders Julie, Brull David, Cooper Jackie, Woo Patricia, Miller George, Rubinstein Menachem, Humphries Steve E

Abstract excerpt

OBJECTIVE: To investigate free interleukin-18 (fIL-18) levels, and variation within the IL-18 system genes, in heart surgery patients, and healthy men. METHODS AND RESULTS: fIL-18 was calculated from IL-18 and IL-18 binding protein (BP) levels, in 421 healthy men and 196 post-coronary artery bypass graft (CABG) patients. After surgery, fIL-18 peaked at 6 hours (from 117 to 331 pg/mL) but fell to below presurgery...

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PMID: 17951325
DOI: 10.1161/ATVBAHA.107.149245

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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