Article
IL-18 gene polymorphism, cardiovascular mortality and coronary artery disease.
European journal of clinical investigation - 1 Nov 2010
Hernesniemi Jussi A, Anttila Kaisa, Nieminen Tuomo, Kähönen Mika, Mononen Nina, Nikus Kjell, Turjanmaa Väinö, Viik Jari, Lehtinen Rami, Lehtimäki Terho
Abstract excerpt
BACKGROUND: Interleukin 18(IL-18) is a pro-atherosclerotic cytokine. Elevated IL-18 levels and the genetic variation of the IL-18 have been previously linked with acute coronary events and cardiovascular mortality among patients with coronary artery disease (CAD). We studied the possible association between the IL-18 gene polymorphism and cardiovascular mortality during follow-up among Finnish patients who had...
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