Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL18 haplotypes are associated with serum IL-18 concentrations in a population-based study and a cohort of individuals with premature coronary heart disease.

Clinical chemistry - 1 Dec 2007

Thompson Simon R, McCaskie Pamela A, Beilby John P, Hung Joseph, Jennens Michelle, Chapman Caroline, Thompson Peter, Humphries Steve E

Abstract excerpt

BACKGROUND: Interleukin (IL)-18 is a proinflammatory cytokine that has been implicated in several diseases, including atherosclerosis, and increased circulating IL-18 concentrations increase risk of future coronary heart disease (CHD). We evaluated the effect of common variation within the IL18 gene on concentrations of circulating IL-18. METHODS: We measured IL-18, by ELISA, in the population-based study group...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cohort Studies
Share to Coronary Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cross-Sectional Studies

Share to Haplotypes

Share to Interleukin-18

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 17962365
DOI: 10.1373/clinchem.2007.092692

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL18 haplotypes are associated with serum IL-18 concentrations in a population-based study and a cohort of individuals with premature coronary heart disease.PMID 17962365Read ↗

Genetic analysis of the interleukin-18 system highlights the role of the interleukin-18 gene in cardiovascular disease.Semantic proximity Read ↗

Circulating levels of IL-18 are significantly influenced by the IL-18 +183 A/G polymorphism in coronary artery disease patients with diabetes type 2 and the metabolic syndrome: an observational study.Semantic proximity Read ↗

Haplotypic analysis of tag SNPs of the interleukin-18 gene in relation to cardiovascular disease events: the MORGAM Project.Semantic proximity Read ↗

The frequency of an IL-18-associated haplotype in Africans.Semantic proximity Read ↗

Genotyping of interleukins-18 promoters and their correlation with coronary artery stenosis in Saudi population.Semantic proximity Read ↗

IL-18 gene polymorphism, cardiovascular mortality and coronary artery disease.Semantic proximity Read ↗

Lack of association between polymorphisms of the IL18R1 and IL18RAP genes and cardiovascular risk: the MORGAM Project.Semantic proximity Read ↗

Association of IL-18 gene polymorphisms with clinical aspects of hyperlipidemia in middle-aged and early people in the community.Semantic proximity Read ↗

A common interleukin 18 haplotype is associated with higher body mass index in subjects with diabetes and coronary heart disease.Semantic proximity Read ↗

Interleukin-17A gene haplotypes are associated with risk of premature coronary artery disease in Mexican patients from the Genetics of Atherosclerotic Disease (GEA) study.Semantic proximity Read ↗

Variation in inflammation-related genes and risk of incident nonfatal myocardial infarction or ischemic stroke.Semantic proximity Read ↗

Genetic variation within IL18 is associated with insulin levels, insulin resistance and postprandial measures.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.