Article
Interleukin 18 and coronary heart disease: prospective study and systematic review.
Atherosclerosis - 1 Jul 2011
Jefferis Barbara J M H, Papacosta Olia, Owen Christopher G, Wannamethee S Goya, Humphries Steve E, Woodward Mark, Lennon Lucy T, Thomson Andrew, Welsh Paul, Rumley Ann, Lowe Gordon D O, Whincup Peter H
Abstract excerpt
AIM: Previous studies suggest that circulating levels of interleukin-18 (IL-18) may be prospectively related to risk of coronary heart disease (CHD) in the general population. We report new data from the largest prospective study to date, which are combined with data from all published prospective studies in a meta-analysis. METHODS: We measured baseline IL-18 levels in stored serum samples of subjects from a...
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