Article
Glycine residues G338 and G342 are important determinants for serotonin transporter dimerisation and cell surface expression.
Neurochemistry international - 1 Jan 2000
Horschitz Sandra, Lau Thorsten, Schloss Patrick
Abstract excerpt
Compelling evidence has been provided that Na(+) and Cl(-)-dependent neurotransmitter transporter proteins form oligomeric complexes. Specific helix-helix interactions in lipid bilayers are thought to promote the assembly of integral membrane proteins to oligomeric structures. These interactions are determined by selective transmembrane helix packing motifs one of which is the Glycophorin A motif (GxxxG). This...
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