Article
Serotonin type 4 receptor dimers.
Methods in cell biology - 1 Jan 2013
Claeysen Sylvie, Donneger Romain, Giannoni Patrizia, Gaven Florence, Pellissier Lucie P
Abstract excerpt
Numerous class A G protein-coupled receptors and especially biogenic amine receptors have been reported to form homodimers. Indeed, the dimerization process might occur for all the metabotropic serotonergic receptors. Moreover, dimerization appears to be essential for the function of serotonin type 2C (5-HT2C) and type 4 (5-HT4) receptors and required to obtain full receptor activity. Several techniques have been...
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