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Article

The cellular distribution of serotonin transporter is impeded on serotonin-altered vimentin network.

PloS one - 1 Jan 2009

Ahmed Billow A, Bukhari Irfan A, Jeffus Brandon C, Harney Justin T, Thyparambil Sheeno, Ziu Endrit, Fraer Mony, Rusch Nancy J, Zimniak Piotr, Lupashin Vladimir, Tang Dale, Kilic Fusun

Abstract excerpt

BACKGROUND: The C-terminus of the serotonin transporter (SERT) contains binding domains for different proteins and is critical for its functional expression. In endogenous and heterologous expression systems, our proteomic and biochemical analysis demonstrated that an intermediate filament, vimentin, binds to the C-terminus of SERT. It has been reported that 5HT-stimulation of cells leads to disassembly and...

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Identifiers

PMID: 19270731
DOI: 10.1371/journal.pone.0004730
PMCID: PMC2648896

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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