Article
Functional consequences of homo- but not hetero-oligomerization between transporters for the biogenic amine neurotransmitters.
Journal of neurochemistry - 1 Jun 2003
Kocabas A M, Rudnick G, Kilic F
Abstract excerpt
Before this study, the human norepinephrine transporter (hNET) was the only member of the biogenic amine neurotransmitter transporter family that had not been demonstrated to be a functional homo-oligomer. Here, using two forms of the transporter, I155C and hNET-myc, with distinct antigenicity and inhibitor sensitivity, we demonstrated that hNET exists as a homo-oligomer. hNET I155C is a functional mutant and is...
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