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Article

"AKT"ing lessons for stem cells: regulation of cardiac myocyte and progenitor cell proliferation.

Trends in cardiovascular medicine - 1 Oct 2007

Sussman Mark

Abstract excerpt

Cardiac development and postnatal growth depend on activation of AKT, but initial strategies to improve myocardial repair using AKT were stymied by undesirable corollary alterations in myocardial structure and function. These unfortunate precedents were based on high-level expression of constitutively activated AKT, predominantly in the cytoplasm of the cell. Based on subsequent studies establishing that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17936205
DOI: 10.1016/j.tcm.2007.08.003
PMCID: PMC2083554

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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