Article
Cardiac progenitor cell cycling stimulated by pim-1 kinase.
Circulation research - 19 Mar 2010
Cottage Christopher T, Bailey Brandi, Fischer Kimberlee M, Avitabile Daniele, Avitable Daniele, Collins Brett, Tuck Savilla, Quijada Pearl, Gude Natalie, Alvarez Roberto, Muraski John, Sussman Mark A
Abstract excerpt
RATIONALE: Cardioprotective effects of Pim-1 kinase have been previously reported but the underlying mechanistic basis may involve a combination of cellular and molecular mechanisms that remain unresolved. The elucidation of the mechanistic basis for Pim-1 mediated cardioprotection provides important insights for designing therapeutic interventional strategies to treat heart disease. OBJECTIVE: Effects of...
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