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Article

Neurotrophic factor receptor RET: structure, cell biology, and inherited diseases.

Annals of medicine - 1 Jan 2007

Runeberg-Roos Pia, Saarma Mart

Abstract excerpt

RET (REarranged during Transfection) is a transmembrane receptor tyrosine kinase that is activated by a complex consisting of a soluble glial cell line-derived neurotrophic factor (GDNF) family ligand (GFL) and a glycosyl phosphatidylinositol-anchored co-receptor, GDNF family receptors alpha (GFRalpha). RET signalling is crucial for the development of the enteric nervous system. RET also regulates the development...

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Source

Identifiers

PMID: 17934909
DOI: 10.1080/07853890701646256

Genes

RET
GDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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