RET and neuroendocrine tumors.

Abstract excerpt

Glial cell line-derived neurotrophic factor (GDNF), a ligand of RET tyrosine kinase, and its family ligands promote the survival and differentiation of a variety of neurons. Gene ablation studies have revealed that the GDNF-RET receptor system is essential for the development of kidney and peripheral neurons, including sympathetic, parasympathetic and enteric neurons. RET can activate various signaling pathways...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Drosophila Proteins
• Share to Gene Expression Regulation
• Share to Glial Cell Line-Derived Neurotrophic Factor