Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RET receptor signaling: Function in development, metabolic disease, and cancer

10 Mar 2022

Abstract excerpt

The RET proto-oncogene encodes a receptor tyrosine kinase whose alterations are responsible for various human cancers and developmental disorders, including thyroid cancer, non-small cell lung cancer, multiple endocrine neoplasia type 2, and Hirschsprung's disease. RET receptors are physiologically activated by glial cell line-derived neurotrophic factor (GDNF) family ligands that bind to the coreceptor GDNF...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circular RNAs in diseases
Share to GDF15 and Related Biomarkers
Share to Nutrition and Health in Aging

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35283407
DOI: 10.2183/pjab.98.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RET receptor signaling: Function in development, metabolic disease, and cancerPMID 35283407Read ↗

Overview of growth differentiation factor 15 in metabolic syndromeSemantic proximity Read ↗

Neurotrophic factor receptor RET: structure, cell biology, and inherited diseases.Semantic proximity Read ↗

Insights Into Mechanisms of GDF15 and Receptor GFRAL: Therapeutic TargetsSemantic proximity Read ↗

RET Receptor Tyrosine Kinase: Role in Neurodegeneration, Obesity, and Cancer.Semantic proximity Read ↗

GDF15 as a key disease target and biomarker: linking chronic lung diseases and ageingSemantic proximity Read ↗

The GDNF/RET signaling pathway and human diseasesSemantic proximity Read ↗

GDF15 and Growth ControlSemantic proximity Read ↗

Role of Growth Differentiation Factor 15 in Lung Disease and Senescence: Potential Role Across the LifespanSemantic proximity Read ↗

Current concepts in RET-related genetics, signaling and therapeutics.Semantic proximity Read ↗

RET and neuroendocrine tumors.Semantic proximity Read ↗

RET and neuroendocrine tumors.Semantic proximity Read ↗

RET receptor signaling: dysfunction in thyroid cancer and Hirschsprung's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.