Article
Characterization of HLA class I altered phenotypes in a panel of human melanoma cell lines.
Cancer immunology, immunotherapy : CII - 1 May 2008
Méndez Rosa, Rodríguez Teresa, Del Campo Ana, Monge Eva, Maleno Isabel, Aptsiauri Natalia, Jiménez Pilar, Pedrinaci Susana, Pawelec Graham, Ruiz-Cabello Francisco, Garrido Federico
Abstract excerpt
BACKGROUND: Altered HLA class I cell surface expression is one of the major mechanisms by which tumor cells escape from T lymphocytes. Immunohistochemistry-defined phenotypes of lost HLA class I expression have been described in human solid tumors, nut less information is available on melanoma cell lines. OBJECTIVES: To describe the frequency and distribution of different types of HLA class I antigen alterations...
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