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Article

Different mechanisms can lead to the same altered HLA class I phenotype in tumors.

Tissue antigens - 1 Apr 2007

Rodriguez T, Aptsiauri N, Méndez R, Jimenez P, Ruiz-Cabello F, Garrido F

Abstract excerpt

Human leukocyte antigen (HLA) class I plays an important role in tumor recognition and rejection. Total or selective losses of HLA class I antigens (classified into seven HLA class I altered phenotypes) represent one of the main routes of tumor escape from immune surveillance. Abnormal expression of HLA class I has been reported in different human tumor samples with distinct underlying mechanisms. Notably,...

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Identifiers

PMID: 17445215
DOI: 10.1111/j.1399-0039.2006.00776.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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