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Assessment of cancer cell‐expressed HLA class I molecules and their immunopathological implications

1 May 2024

Abstract excerpt

Immunotherapy using immune checkpoint inhibitors (ICIs) has shown superior efficacy compared with conventional chemotherapy in certain cancer types, establishing immunotherapy as the fourth standard treatment alongside surgical intervention, chemotherapy, and radiotherapy. In cancer immunotherapy employing ICIs, CD8-positive cytotoxic T lymphocytes are recognized as the primary effector cells. For effective...

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PMID: 38699870
DOI: 10.1111/tan.15472

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