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Article

Role of altered expression of HLA class I molecules in cancer progression.

Advances in experimental medicine and biology - 1 Jan 2007

Aptsiauri Natalia, Cabrera Teresa, Mendez Rosa, Garcia-Lora Angel, Ruiz-Cabello Francisco, Garrido Federico

Abstract excerpt

HLA class I antigens play a key role in immune recognition of transformed and virally infected cells via binding to the peptides of "non-self" or aberrantly expressed proteins and subsequent presentation of the newly formed "HLA-I-peptide" complex to T lymphocytes. Consequently, a chain of immune reactions is initiated leading to tumor cell elimination by cytotoxic T cells. Altered tumor expression of HLA class I...

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Source

Identifiers

PMID: 17712999
DOI: 10.1007/978-0-387-72005-0_13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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