Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Effect of UGT1A6 genetic polymorphisms on the metabolism of sodium valproate].

Zhonghua yi xue za zhi - 7 Aug 2007

Sun Yan-ping, Tan Lan, Wang Yan, Song Jing-hui

Abstract excerpt

OBJECTIVE: To investigate the effect of UGT1A6 genetic polymorphisms on the serum concentration of sodium valproate so as to help better individualize the medication for patients with epilepsy. METHODS: Peripheral blood samples were collected for 67 patients receiving sodium valproate after more than 5 half-time periods, aged 17.5 (5 - 52). The genotypes of UGT1A6 were detected by polymerase chain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child, Preschool
Share to Epilepsy
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucuronosyltransferase

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to Valproic Acid

Share to Young Adult

Source

Identifiers

PMID: 17925173

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Effect of UGT1A6 genetic polymorphisms on the metabolism of sodium valproate].PMID 17925173Read ↗

The effect of uridine diphosphate glucuronosyltransferase (UGT)1A6 genetic polymorphism on valproic acid pharmacokinetics in Indian patients with epilepsy: a pharmacogenetic approach.Semantic proximity Read ↗

Association of UGT1A6 gene polymorphism with clinical outcome in pediatric epileptic patients on sodium valproate monotherapy.Semantic proximity Read ↗

Prevalence of UGT1A6 polymorphisms in children with epilepsy on valproate monotherapy.Semantic proximity Read ↗

Effect of UGT2B7 genetic variants on serum valproic acid concentration.Semantic proximity Read ↗

UGT1A6 and UGT2B7 Gene Polymorphism and its Effect in Pediatric Epileptic Patients on Sodium Valproate Monotherapy.Semantic proximity Read ↗

Effect of UGT1A6 and UGT2B7 polymorphisms on the valproic acid serum concentration and drug-induced liver injury.Semantic proximity Read ↗

UGT1A6- and UGT2B7-related valproic acid pharmacogenomics according to age groups and total drug concentration levels.Semantic proximity Read ↗

Association of genetic variants in six candidate genes with valproic acid therapy optimization.Semantic proximity Read ↗

Association of UGT1A6 gene polymorphisms with sodium valproate-induced tremor in patients with epilepsy.Semantic proximity Read ↗

Influence of UGT2B7 and UGT1A6 polymorphisms on plasma concentration to dose ratio of valproic acid in Chinese epileptic children.Semantic proximity Read ↗

Impact of MDR1 and UGT Gene Polymorphisms on Sodium Valproate Plasma Concentration in Patients with Epilepsy.Semantic proximity Read ↗

Effect of UGT2B7 genotypes on plasma concentration of valproic acid: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.