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Article

Association of UGT1A6 gene polymorphisms with sodium valproate-induced tremor in patients with epilepsy.

Seizure - 1 Aug 2024

Yin Zheng, Li Pei

Abstract excerpt

BACKGROUND: Individual susceptibility to sodium valproate (VPA)-induced tremors may be due to genetic polymorphisms in the gene encoding the uridine diphosphate glucuronosyltransferase (UGT) enzyme, which affec the drug's clinical efficacy and cause toxic side effects. This study aimed to investigate the association between UGT1A6 polymorphisms and VPA-induced tremors in patients with epilepsy. METHODS: In total,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38908142
DOI: 10.1016/j.seizure.2024.06.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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