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Article

UGT1A6- and UGT2B7-related valproic acid pharmacogenomics according to age groups and total drug concentration levels.

Pharmacogenomics - 1 Jun 2016

Chatzistefanidis Dimitrios, Lazaros Leandros, Giaka Katerina, Nakou Iliada, Tzoufi Meropi, Georgiou Ioannis, Kyritsis Athanassios, Markoula Sofia

Abstract excerpt

AIM: The role of UGT1A6 and UGT2B7 polymorphisms and the impact of total drug plasma concentration in valproic acid (VPA) pharmacogenomics. PATIENTS & METHODS: A total of 134 Greek patients were recruited (76 adults). Patients were genotyped for UGT1A6 19T>G, 541A>G and 552A>C and UGT2B7 802T>C polymorphisms. Patients' demographic and clinical data were registered. Natural logarithm of concentration-to-dose ratio...

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Source

Identifiers

PMID: 27232006
DOI: 10.2217/pgs-2016-0014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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