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Article

DNA polymerase theta (POLQ) can extend from mismatches and from bases opposite a (6-4) photoproduct.

DNA repair - 1 Jan 2008

Seki Mineaki, Wood Richard D

Abstract excerpt

DNA polymerase theta (pol theta) is a nuclear A-family DNA polymerase encoded by the POLQ gene in vertebrate cells. The biochemical properties of pol theta and of Polq-defective mice have suggested that pol theta participates in DNA damage tolerance. For example, pol theta was previously found to be proficient not only in incorporation of a nucleotide opposite a thymine glycol or an abasic site, but also extends...

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Source

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Identifiers

PMID: 17920341
DOI: 10.1016/j.dnarep.2007.08.005
PMCID: PMC2185714

Genes

POLQ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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