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DNA polymerase iota-dependent translesion replication of uracil containing cyclobutane pyrimidine dimers.

DNA repair - 3 Feb 2006

Vaisman Alexandra, Takasawa Kohei, Iwai Shigenori, Woodgate Roger

Abstract excerpt

Analysis of the spectrum of UV-induced mutations generated in synchronized wild-type S-phase cells reveals that only approximately 25% of mutations occur at thymine (T), whilst 75% are targeted to cytosine (C). The mutational spectra changes dramatically in XP-V cells, devoid of poleta, where app...

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PMID: 16263340
DOI: 10.1016/j.dnarep.2005.09.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16263340-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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