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Which DNA polymerases are used for DNA-repair in eukaryotes?

1 Apr 1997

Abstract excerpt

There are five well-characterized nuclear DNA polymerases in eukaryotes (DNA polymerases alpha, beta, delta, epsilon and zeta) and this short review summarizes our current knowledge concerning the participation of each in DNA-repair. The three major DNA excision-repair pathways involve a DNA synthesis step that replaces altered bases or nucleotides removed during repair. Base excision-repair removes many modified...

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PMID: 9111189
DOI: 10.1093/carcin/18.4.605

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