Article
The functional consequence of the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene in young healthy volunteers.
Cardiovascular drug reviews - 1 Jan 2007
Godfrey Valerie, Chan Sue-Lyn, Cassidy Andrew, Butler Robert, Choy AnnaMaria, Fardon Tom, Struthers Allan, Lang Chim
Abstract excerpt
OBJECTIVE: To assess the role of the endothelial nitric oxide synthase (eNOS) gene variant as a risk factor for atherosclerosis we sought to investigate whether the Glu298Asp polymorphism of the eNOS gene is associated with functional changes in the endothelium in healthy volunteers. METHODS: Endothelial function was assessed in 68 normal volunteers (ages 18-44 years) by bilateral forearm venous occlusion...
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