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Article

Positional cloning of the mouse saccharin preference (Sac) locus.

Chemical senses - 1 Sept 2001

Bachmanov A A, Li X, Reed D R, Ohmen J D, Li S, Chen Z, Tordoff M G, de Jong P J, Wu C, West D B, Chatterjee A, Ross D A, Beauchamp G K

Abstract excerpt

Differences in sweetener intake among inbred strains of mice are partially determined by allelic variation of the saccharin preference (Sac) locus. Genetic and physical mapping limited a critical genomic interval containing Sac to a 194 kb DNA fragment. Sequencing and annotation of this region identified a gene (Tas1r3) encoding the third member of the T1R family of putative taste receptors, T1R3. Introgression...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11555487
DOI: 10.1093/chemse/26.7.925
PMCID: PMC3644801

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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